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Preface
Organization
Contents – Part IV
Computer Assisted Interventions: Image Guided Interventions and Surgery
Uncertainty in Multitask Learning: Joint Representations for Probabilistic MR-only Radiotherapy Planning
1 Introduction
2 Methods
3 Experiments and Results
4 Conclusions
References
A Combined Simulation and Machine Learning Approach for Image-Based Force Classification During Robotized Intravitreal Injections
1 Introduction
2 Method
2.1 Numerical Simulation for Fast Data Generation
2.2 Neural Network Image Classification
3 Results
3.1 Experimental Set-Up
3.2 Data Generation for Neural Network Training
3.3 Tests on Unseen Data
4 Conclusion and Discussion
References
Learning from Noisy Label Statistics: Detecting High Grade Prostate Cancer in Ultrasound Guided Biopsy
1 Introduction
2 Materials
3 Method
3.1 Discriminative Model
3.2 Cancer Grading and Tumor in Core Length Estimation
3.3 Model Uncertainty Estimation
4 Experiments and Results
5 Conclusion
References
A Feature-Driven Active Framework for Ultrasound-Based Brain Shift Compensation
1 Introduction
2 Method
2.1 The Role of US-to-US Registration
2.2 Feature-Based Registration Strategy
2.3 GP Kernel Estimation
3 Experiments
4 Discussion
References
Soft-Body Registration of Pre-operative 3D Models to Intra-operative RGBD Partial Body Scans
1 Introduction, Background and Contributions
2 Methods
2.1 Biomechanical Model Description
2.2 Intra-operative Patient Scanning and Segmentation
2.3 Registration Problem Formulation
2.4 Optimization and Initialization
3 Experimental Results
3.1 Quantitative Analysis with Porcine Datasets
3.2 Qualitative Analysis with a Human Patient
4 Conclusion
References
Automatic Classification of Cochlear Implant Electrode Cavity Positioning
Abstract
1 Introduction
2 Methods
3 Results
4 Conclusions
Acknowledgements
References
X-ray-transform Invariant Anatomical Landmark Detection for Pelvic Trauma Surgery
1 Introduction
2 Method
3 Experiments and Results
3.1 Synthetic X-Rays
3.2 Real X-Rays
4 Discussion and Conclusions
References
Endoscopic Navigation in the Absence of CT Imaging
1 Introduction
2 Method
3 Experimental Results and Discussion
3.1 Experiment 1: Simulation
3.2 Experiment 2: In-Vivo
4 Conclusion
References
A Novel Mixed Reality Navigation System for Laparoscopy Surgery
Abstract
1 Introduction
2 Mixed Reality Navigation for Laparoscopy Surgery
2.1 Mixed-Reality Head Mounted Display (HMD)
2.2 Mixed Reality Navigation Software
2.3 Audio Navigation System
3 Experimental Methods
4 Results and Discussion
5 Conclusion
References
Respiratory Motion Modelling Using cGANs
1 Introduction
2 Method
2.1 Data Acquisition and Image Registration
2.2 Training of the Neural Network
2.3 Real-Time Prediction of Deformation Fields and Stacking
3 Experiments and Results
4 Discussion and Conclusion
References
Physics-Based Simulation to Enable Ultrasound Monitoring of HIFU Ablation: An MRI Validation
1 Introduction
2 Methods
2.1 Biophysical Modeling of HIFU Thermal Ablation
2.2 Ultrasound Thermal Monitoring
3 Experiments and Results
3.1 Sensitivity Analysis
3.2 Phantom Feasibility Study
4 Discussion and Conclusion
References
DeepDRR – A Catalyst for Machine Learning in Fluoroscopy-Guided Procedures
1 Introduction
2 Methods
2.1 Background and Requirements
2.2 DeepDRR
3 Experiments and Results
3.1 Framework Validation
3.2 Task-Based Evaluation
4 Discussion and Conclusion
References
Exploiting Partial Structural Symmetry for Patient-Specific Image Augmentation in Trauma Interventions
1 Introduction
2 Materials and Methods
2.1 Problem Formulation
2.2 Robust Loss for Estimation of Partial Symmetry
2.3 Bone Density Histogram Regularization
2.4 Patient-Specific Image Augmentation
3 Experimental Validation and Results
4 Discussion and Conclusion
References
Intraoperative Brain Shift Compensation Using a Hybrid Mixture Model
1 Introduction
2 Materials and Methods
3 Experiments and Results
4 Discussion and Conclusion
References
Video-Based Computer Aided Arthroscopy for Patient Specific Reconstruction of the Anterior Cruciate Ligament
1 Introduction
2 Video-Based Computer-Aided Arthroscopy
3 Surgical Workflow and Algorithmic Modules
4 Experiments
4.1 Lens Rotation
4.2 3D Registration
5 Conclusions
References
Simultaneous Segmentation and Classification of Bone Surfaces from Ultrasound Using a Multi-feature Guided CNN
1 Introduction
2 Proposed Method
2.1 Enhancement of Bone Surface and Bone Shadow Information
2.2 Pre-enhancing Network (PE)
2.3 Joint Learning of Classification and Segmentation
2.4 Data Acquisition and Training
3 Experimental Results
4 Conclusion
References
Endoscopic Laser Surface Scanner for Minimally Invasive Abdominal Surgeries
1 Introduction
2 Methods and Materials
2.1 Laser Beam Calibration
2.2 Surface Reconstruction as Line-to-Plane Intersection
2.3 Validation
3 Results
4 Discussion and Conclusion
References
Deep Adversarial Context-Aware Landmark Detection for Ultrasound Imaging
1 Introduction
2 Methods
2.1 Baseline Approach for Landmark Detection
2.2 Multitask Learning for Joint Landmark and Contour Detection
3 Results and Discussion
References
Towards a Fast and Safe LED-Based Photoacoustic Imaging Using Deep Convolutional Neural Network
1 Introduction
2 Methods
2.1 Architecture
2.2 Loss Function
3 Experiments and Materials
3.1 LED Excitation Source
3.2 Data Acquisition
3.3 Materials
3.4 Training
4 Evaluation and Results
4.1 Peak Signal-to-Noise-Ratio and Structural Similarity Index
4.2 Performance at Different Depths
4.3 Qualitative Analysis
4.4 Computation Time
5 Discussion and Conclusion
References
An Open Framework Enabling Electromagnetic Tracking in Image-Guided Interventions
1 Introduction
2 Framework Design
3 Framework Implementation
4 Experiments and Results
4.1 Performance Benchmark
4.2 Accuracy Benchmark
5 Discussion
6 Conclusion
References
Colon Shape Estimation Method for Colonoscope Tracking Using Recurrent Neural Networks
1 Introduction
2 Colon Shape Estimation Method
2.1 Overview
2.2 Colon and Colonoscope Shape Representation
2.3 Colonoscope Shape Features
2.4 Shape Estimation Network
3 Experimental Setup
3.1 Colonoscope Shape Measurement
3.2 Colon Shape Measurement
3.3 Shape Estimation Network Training
3.4 Colon Shape Estimation
3.5 Evaluation Metric
4 Experimental Results
5 Discussion
References
Towards Automatic Report Generation in Spine Radiology Using Weakly Supervised Framework
1 Introduction
2 The Proposed Framework for Report Generation
2.1 Recurrent Generative Adversarial Network
2.2 Prior Knowledge-Based Symbolic Program Synthesis
3 Results
4 Discussion and Conclusion
References
Computer Assisted Interventions: Surgical Planning, Simulation and Work Flow Analysis
A Natural Language Interface for Dissemination of Reproducible Biomedical Data Science
1 Introduction
2 Archetypal Analysis Scenarios
3 The Core System Architecture
4 Conclusion
References
Spatiotemporal Manifold Prediction Model for Anterior Vertebral Body Growth Modulation Surgery in Idiopathic Scoliosis
1 Introduction
2 Method
2.1 Discriminant Embedding of Longitudinal Spine Models
2.2 Piecewise-Geodesic Spatiotemporal Manifold
2.3 Prediction of Spine Correction
3 Experiments
4 Conclusion
References
Evaluating Surgical Skills from Kinematic Data Using Convolutional Neural Networks
1 Introduction
2 Method
2.1 Dataset
2.2 Architecture
2.3 Training and Testing
2.4 Class Activation Map
3 Results
3.1 Surgical Skill Classification
3.2 Feedback Visualization
4 Conclusion
References
Needle Tip Force Estimation Using an OCT Fiber and a Fused convGRU-CNN Architecture
1 Introduction
2 Materials and Methods
2.1 Needle Design and Experimental Setup
2.2 Model Architecture
2.3 Data Acquisition and Datasets
3 Results
4 Discussion
5 Conclusion
References
Fast GPU Computation of 3D Isothermal Volumes in the Vicinity of Major Blood Vessels for Multiprobe Cryoablation Simulation
1 Introduction
2 Materials and Methods
2.1 General Formulation
2.2 Propagation of Cold in the Human Body Near Heating Sources
2.3 Validation in Silico
2.4 Validation on Intraoperative MRI Images
3 Results
4 Conclusion
References
A Machine Learning Approach to Predict Instrument Bending in Stereotactic Neurosurgery
1 Introduction
2 Methods
3 Experimental Design and Validation
4 Conclusion
References
Deep Reinforcement Learning for Surgical Gesture Segmentation and Classification
1 Introduction
2 Preliminary
3 Proposed Method
4 Experiments
5 Conclusion and Future Work
References
Automated Performance Assessment in Transoesophageal Echocardiography with Convolutional Neural Networks
1 Introduction
2 Methods
2.1 Dataset Generation
2.2 CNN Architectures
3 Experimentation and Results
4 Conclusions
References
DeepPhase: Surgical Phase Recognition in CATARACTS Videos
1 Introduction
2 Materials and Methods
2.1 Augmented CATARACT Dataset
2.2 Tool Recognition with CNNs
2.3 Phase Recognition with RNNs
3 Experimental Results
3.1 Evaluation Metrics
3.2 Tool Recognition
3.3 Phase Recognition
4 Discussion and Conclusion
References
Surgical Activity Recognition in Robot-Assisted Radical Prostatectomy Using Deep Learning
1 Introduction
2 Methodology
3 Experimental Evaluation
4 Results and Discussion
5 Conclusion
References
Unsupervised Learning for Surgical Motion by Learning to Predict the Future
1 Introduction
2 Methods
2.1 Recurrent Neural Networks and Long Short-Term Memory
2.2 The RNN Encoder-Decoder
2.3 Mixture Density Networks
2.4 Training
3 Experiments
3.1 Dataset
3.2 Future Prediction
3.3 Information Retrieval with Motion-Based Queries
4 Summary and Future Work
References
Computer Assisted Interventions: Visualization and Augmented Reality
Volumetric Clipping Surface: Un-occluded Visualization of Structures Preserving Depth Cues into Surrounding Organs
1 Introduction
1.1 Focus+Context
1.2 Clinical Application
2 Existing Techniques
2.1 Clipping Planes
2.2 Cut-Aways
3 A Real-Time Depth Contiguous Clipping Surface
3.1 Methodology
3.2 Computational Complexity
4 Simulation
5 Conclusions
References
Closing the Calibration Loop: An Inside-Out-Tracking Paradigm for Augmented Reality in Orthopedic Surgery
1 Introduction
2 Materials and Methods
2.1 Calibration
2.2 Prototype
2.3 Virtual Content in the AR Environment
2.4 Experiments and Feasibility Study
3 Results
4 Discussion and Conclusion
References
Higher Order of Motion Magnification for Vessel Localisation in Surgical Video
1 Introduction
2 Methods
2.1 Temporal Filtering
2.2 Phase-Based Magnification
3 Results
4 Conclusion
References
Simultaneous Surgical Visibility Assessment, Restoration, and Augmented Stereo Surface Reconstruction for Robotic Prostatectomy
1 Endoscopic Vision
2 Approaches
2.1 Visibility Assessment
2.2 Visualization Restoration
2.3 Augmented Disparity
3 Validation
4 Results and Discussion
5 Conclusions
References
Real-Time Augmented Reality for Ear Surgery
1 Introduction
2 Methodology
2.1 Initial Semi-automatic Endosocope-CT Registration
2.2 Endoscope-Target Motion Tracking
2.3 3D Pose Estimation of Surgical Instrument
3 Experimental Setup and Results
4 Conclusion
References
Framework for Fusion of Data- and Model-Based Approaches for Ultrasound Simulation
1 Introduction
2 Methods
2.1 Data-Based: Realistic Background from Images
2.2 Model-Based Simulation: Detailed, Arbitrary Content
2.3 Tissue Deformations
2.4 Texture Filling
2.5 Compounding Contents
3 Results
4 Conclusions
References
Image Segmentation Methods: General Image Segmentation Methods, Measures and Applications
Esophageal Gross Tumor Volume Segmentation Using a 3D Convolutional Neural Network
1 Introduction
2 Proposed Network Architecture
3 Materials and Implementation
3.1 Dataset
3.2 Augmentation and Training Details
4 Experiments and Results
5 Discussion and Conclusion
References
Deep Learning Based Instance Segmentation in 3D Biomedical Images Using Weak Annotation
1 Introduction
2 Method
2.1 3D Object Detector Using 3D Bounding Box Annotation
2.2 3D Voxel Segmentation Using Full Voxel Annotation for a Small Fraction of Instances
3 Experiments and Results
4 Conclusions
References
Learn the New, Keep the Old: Extending Pretrained Models with New Anatomy and Images
1 Introduction
2 Incremental Head Networks
2.1 Conservation of Prior Knowledge with Distillation
2.2 Selecting Representative Samples
3 Experiments and Results
4 Discussions
5 Conclusions
References
ASDNet: Attention Based Semi-supervised Deep Networks for Medical Image Segmentation
1 Introduction
2 Method
2.1 Segmentation Network with Sample Attention
2.2 Confidence Network for Fully Convolutional Adversarial Learning
2.3 Region-Attention Based Semi-supervised Learning
2.4 Implementation Details
3 Experiments and Results
3.1 Comparison with State-of-the-art Methods
3.2 Impact of Each Proposed Component
3.3 Validation on Another Dataset
4 Conclusions
References
MS-Net: Mixed-Supervision Fully-Convolutional Networks for Full-Resolution Segmentation
1 Introduction and Related Work
2 Methods
3 Results and Discussion
References
How to Exploit Weaknesses in Biomedical Challenge Design and Organization
1 Introduction
2 Methods
3 Results
4 Discussion
References
Accurate Weakly-Supervised Deep Lesion Segmentation Using Large-Scale Clinical Annotations: Slice-Propagated 3D Mask Generation from 2D RECIST
1 Introduction
2 Method
2.1 Initial RECIST-Slice Segmentation
2.2 RECIST-Slice Segmentation
2.3 Weakly Supervised Slice-Propagated Segmentation
3 Materials and Results
3.1 Initial RECIST-Slice Segmentation
3.2 CNN Based RECIST-Slice Segmentation
3.3 Weakly Supervised Slice-Propagated Segmentation
4 Conclusion
References
Semi-automatic RECIST Labeling on CT Scans with Cascaded Convolutional Neural Networks
1 Introduction
2 Methodology
2.1 Lesion Region Normalization
2.2 RECIST Estimation
2.3 Model Optimization
3 Experimental Results and Analyses
4 Conclusions
References
Image Segmentation Methods: Multi-organ Segmentation
A Multi-scale Pyramid of 3D Fully Convolutional Networks for Abdominal Multi-organ Segmentation
1 Introduction
2 Methods
2.1 3D Fully Convolutional Networks
2.2 Multi-scale Auto-Context Pyramid Approach
2.3 Implementation and Training
3 Experiments and Results
4 Discussion and Conclusion
References
3D U-JAPA-Net: Mixture of Convolutional Networks for Abdominal Multi-organ CT Segmentation
Abstract
1 Introduction
2 Methods
3 Experiments and Results
4 Discussion
5 Conclusion
Acknowledgements
References
Training Multi-organ Segmentation Networks with Sample Selection by Relaxed Upper Confident Bound
1 Introduction
2 Methodology
2.1 Upper Confident Bound (UCB)
2.2 Relaxed Upper Confident Bound (RUCB) Boostrapping
3 Experimental Results
3.1 Experimental Setup
3.2 Evaluation of RUCB
4 Conclusion
References
Image Segmentation Methods: Abdominal Segmentation Methods
Bridging the Gap Between 2D and 3D Organ Segmentation with Volumetric Fusion Net
1 Introduction
2 Our Approach
2.1 Framework: Fusing 2D Segmentation into a 3D Volume
2.2 Volumetric Fusion Net
2.3 Training and Testing VFN
3 Experiments
3.1 The NIH Pancreas Segmentation Dataset
3.2 Our Multi-organ Dataset
4 Conclusions
References
Segmentation of Renal Structures for Image-Guided Surgery
Abstract
1 Introduction
2 Residual U-Net
2.1 Residual Graphs
2.2 Multi-scale Residual Network
3 Multi-scale Categorical Entropy
4 Experiments
4.1 Data
4.2 Methods and Evaluation
4.3 Results
5 Conclusions
References
Kid-Net: Convolution Networks for Kidney Vessels Segmentation from CT-Volumes
1 Introduction and Related Work
2 Method
3 Experiments
4 Conclusion
References
Local and Non-local Deep Feature Fusion for Malignancy Characterization of Hepatocellular Carcinoma
1 Introduction
2 Method
2.1 Local Deep Feature Extraction
2.2 Non-local Deep Feature Extraction
2.3 Correlation and Individual Feature Analysis
2.4 Local and Nonlocal Deep Feature Fusion Framework
2.5 The Implementation
3 Results
3.1 Subjects, MR Imaging and Histology Information
3.2 Performance of Local and Nonlocal Deep Feature
3.3 Comparison of Deep Feature Fusion Methods
4 Conclusion
References
A Novel Bayesian Model Incorporating Deep Neural Network and Statistical Shape Model for Pancreas Segmentation
1 Introduction
2 Method
2.1 Dense-UNet Segmentation Network
2.2 Bayesian Model
3 Evaluation
4 Discussion
References
Fine-Grained Segmentation Using Hierarchical Dilated Neural Networks
1 Introduction
2 Method
2.1 Hierarchical Dilated Network
2.2 Comparison with ResNet and DenseNet
3 Experiments
4 Conclusion
References
Generalizing Deep Models for Ultrasound Image Segmentation
1 Introduction
2 Methodology
2.1 Architecture of Sub-networks
2.2 Objective Functions for Online Adversarial Rendering
2.3 Optimization and Online Rendering
3 Experimental Results
4 Conclusions
References
Inter-site Variability in Prostate Segmentation Accuracy Using Deep Learning
1 Introduction
2 Methods
2.1 Imaging
2.2 Experimental Design
2.3 Neural Networks: Architectures and Training
3 Results
4 Discussion
References
Deep Learning-Based Boundary Detection for Model-Based Segmentation with Application to MR Prostate Segmentation
1 Introduction
2 Method
3 Results
4 Conclusion
References
Deep Attentional Features for Prostate Segmentation in Ultrasound
1 Introduction
2 Deep Attentional Features for Segmentation
2.1 Method Overview
2.2 Deep Attentional Features
3 Experiments
3.1 Materials
3.2 Training and Testing Strategies
3.3 Segmentation Performance
4 Conclusion
References
Accurate and Robust Segmentation of the Clinical Target Volume for Prostate Brachytherapy
1 Introduction
2 Materials and Methods
2.1 Data
2.2 Clustering of the Training Images
2.3 Proposed CNN Architecture
2.4 Training a CNN Ensemble with Adaptive Sampling
2.5 Improving Uncertain Segmentations Using an SSM
3 Results and Discussion
4 Conclusion
References
Image Segmentation Methods: Cardiac Segmentation Methods
Hashing-Based Atlas Ranking and Selection for Multiple-Atlas Segmentation
1 Introduction
2 Methodology
2.1 Volumetric Ensemble Hashing Through mHF
2.2 Retrieval Through Combinatorial Optimization (CO)
2.3 Similarity Estimation Through Assignment Problem with Dimensionality Reduction
3 Experiments and Results
3.1 Datasets
3.2 Validation Against Baseline
3.3 Validation Against Multi-label V-Net (MLVN)
3.4 Discussion Around Performance and Computational Speed
4 Conclusions
References
Corners Detection for Bioresorbable Vascular Scaffolds Segmentation in IVOCT Images
1 Introduction
2 Method
2.1 Training a Classifier for Corners Detection
2.2 Segmentation Based on Detected Corners
3 Experiments
3.1 Materials and Parameter Settings
3.2 Evaluation Criteria
3.3 Results
4 Conclusion
References
The Deep Poincaré Map: A Novel Approach for Left Ventricle Segmentation
1 Introduction
2 Methodology
2.1 Generating a Customized Dynamic
2.2 Creating a Patch-Policy Predictor Using a CNN
2.3 Stopping Criterion: The Poincaré Map
3 Experimental Setting and Results
4 Conclusion
References
Bayesian VoxDRN: A Probabilistic Deep Voxelwise Dilated Residual Network for Whole Heart Segmentation from 3D MR Images
1 Introduction
2 Methods
3 Experiments and Results
4 Conclusion
References
Real-Time Prediction of Segmentation Quality
1 Introduction
2 Method and Material
3 Results
4 Conclusion
References
Recurrent Neural Networks for Aortic Image Sequence Segmentation with Sparse Annotations
1 Introduction
1.1 Related Works
2 Methods
2.1 Network Architecture
2.2 Label Propagation and Weighted Loss
2.3 Evaluation
3 Experiments and Results
3.1 Data and Annotations
3.2 Implementation and Training
3.3 Network Parameters
3.4 Comparison to Baseline
4 Conclusions
References
Deep Nested Level Sets: Fully Automated Segmentation of Cardiac MR Images in Patients with Pulmonary Hypertension
1 Introduction
2 Modelling Biventricular Anatomy in Patients with PH
3 Methodology
4 Experimental Results
5 Conclusion
References
Atrial Fibrosis Quantification Based on Maximum Likelihood Estimator of Multivariate Images
1 Introduction
2 Method
2.1 MAS for Generating LA Anatomy and Probability Map
2.2 MvMM and MLE for Multivariate Image Segmentation
2.3 Optimization Strategy for Registration in MvMM
2.4 Projection of the Segmentation onto the LA Surface
3 Experiments
3.1 Materials
3.2 Result
4 Conclusion
References
Left Ventricle Segmentation via Optical-Flow-Net from Short-Axis Cine MRI: Preserving the Temporal Coherence of Cardiac Motion
Abstract
1 Introduction
1.1 Left Ventricle Segmentation
1.2 Our Motivation and Contribution
2 Method
2.1 Optical Flow in Cine MRI
2.2 Optical Flow Feature Aggregation
2.3 Optical Flow Net (OF-net)
3 Experiments and Results
3.1 Data and Ground Truth
3.2 Network Parameters and Performance Evaluation
3.3 Results
4 Conclusion
Acknowledgements
References
VoxelAtlasGAN: 3D Left Ventricle Segmentation on Echocardiography with Atlas Guided Generation and Voxel-to-Voxel Discrimination
1 Introduction
2 Methods
2.1 Voxel-to-Voxel cGAN for High-Quality 3D LV Segmentation
2.2 Atlas Guided Generation
2.3 Voxel-to-Voxel Discrimination with Consistent Constraint
3 Dataset and Setting
4 Results and Analysis
5 Conclusions
References
Domain and Geometry Agnostic CNNs for Left Atrium Segmentation in 3D Ultrasound
1 Introduction
2 Methodology
3 Experiments and Results
4 Discussion and Conclusion
References
Image Segmentation Methods: Chest, Lung and Spine Segmentation
Densely Deep Supervised Networks with Threshold Loss for Cancer Detection in Automated Breast Ultrasound
1 Introduction
2 Methods
2.1 Network Architecture
2.2 Densely Deep Supervision
2.3 Threshold Map
3 Experiments
4 Conclusion
References
Btrfly Net: Vertebrae Labelling with Energy-Based Adversarial Learning of Local Spine Prior
1 Introduction
2 Methodology
2.1 Btrfly Network
2.2 Energy-Based Adversary for Encoding Prior
2.3 Inference
3 Experiments
4 Conclusions
References
AtlasNet: Multi-atlas Non-linear Deep Networks for Medical Image Segmentation
1 Introduction
2 Methodology
2.1 Multimetric Deformable Operator
2.2 Segmentation Networks
3 Implementation Details
4 Experimental Results and Dataset
5 Conclusion
References
CFCM: Segmentation via Coarse to Fine Context Memory
1 Introduction and Previous Work
2 Method
2.1 Encoder
2.2 Decoder
3 Experimental Evaluation
4 Conclusion
References
Image Segmentation Methods: Other Segmentation Applications
Pyramid-Based Fully Convolutional Networks for Cell Segmentation
1 Introduction
1.1 Related Work
1.2 Motivation
1.3 Our Proposal
2 Preliminaries
2.1 Fully Convolutional Networks (FCN)
2.2 Gaussian Pyramid and Laplacian Pyramid
3 Methodology
3.1 Pyramid-Based FCNs
3.2 Objective Function and Optimization
4 Experiments
5 Conclusion
References
Automated Object Tracing for Biomedical Image Segmentation Using a Deep Convolutional Neural Network
1 Introduction
2 Data and Methods
2.1 Data
2.2 Network Architectures
2.3 Tracing Algorithm
2.4 Training and Testing Procedure
3 Results
4 Conclusions
References
RBC Semantic Segmentation for Sickle Cell Disease Based on Deformable U-Net
1 Introduction
2 Materials and Methods
3 Results
4 Conclusion
References
Accurate Detection of Inner Ears in Head CTs Using a Deep Volume-to-Volume Regression Network with False Positive Suppression and a Shape-Based Constraint
Abstract
1 Introduction
2 Methods
2.1 Data
2.2 3D U-Net with False Positive Suppression and a Shape Constraint
3 Results
4 Conclusions
Acknowledgments
References
Automatic Teeth Segmentation in Panoramic X-Ray Images Using a Coupled Shape Model in Combination with a Neural Network
1 Introduction
2 Methods
3 Experiments and Results
4 Discussion
5 Conclusion
References
Craniomaxillofacial Bony Structures Segmentation from MRI with Deep-Supervision Adversarial Learning
Abstract
1 Introduction
2 Method
2.1 Simulation GAN
2.2 Segmentation GAN
3 Experimental Results
3.1 Dataset
3.2 Impact of Deep-Supervision Feature Maps
3.3 Impact of Generated CT
3.4 Impact of Pre-trained VGG-16 Network
3.5 Comparison with State-of-the-Art Segmentation Methods
4 Conclusion
References
Automatic Skin Lesion Segmentation on Dermoscopic Images by the Means of Superpixel Merging
1 Introduction
2 Related Work
3 Skin Lesion Segmentation
3.1 Data Set
3.2 Superpixel Segmentation
3.3 Superpixel Merging
3.4 Post-processing
4 Experimental Results
5 Conclusions and Future Work
References
Star Shape Prior in Fully Convolutional Networks for Skin Lesion Segmentation
1 Introduction
2 Methodology
3 Experiments
4 Conclusion
References
Fast Vessel Segmentation and Tracking in Ultra High-Frequency Ultrasound Images
1 Introduction
2 Methods
2.1 Data Acquisition
2.2 Noise Reduction and Clustering
2.3 Local Phase Analysis
2.4 Vessel Segmentation and Tracking
3 Results and Discussion
4 Conclusion and Future Work
References
Deep Reinforcement Learning for Vessel Centerline Tracing in Multi-modality 3D Volumes
1 Introduction
2 Background
3 Method
4 Experiment
4.1 Dataset
4.2 Network Architecture and Implementation
4.3 Evaluation and Discussion
5 Conclusion
References
Author Index
Alejandro F. Frangi · Julia A. Schnabel Christos Davatzikos · Carlos Alberola-López Gabor Fichtinger (Eds.) 3 7 0 1 1 S C N L Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 21st International Conference Granada, Spain, September 16–20, 2018 Proceedings, Part IV 123
Lecture Notes in Computer Science 11073 Commenced Publication in 1973 Founding and Former Series Editors: Gerhard Goos, Juris Hartmanis, and Jan van Leeuwen Editorial Board David Hutchison Lancaster University, Lancaster, UK Takeo Kanade Carnegie Mellon University, Pittsburgh, PA, USA Josef Kittler University of Surrey, Guildford, UK Jon M. Kleinberg Cornell University, Ithaca, NY, USA Friedemann Mattern ETH Zurich, Zurich, Switzerland John C. Mitchell Stanford University, Stanford, CA, USA Moni Naor Weizmann Institute of Science, Rehovot, Israel C. Pandu Rangan Indian Institute of Technology Madras, Chennai, India Bernhard Steffen TU Dortmund University, Dortmund, Germany Demetri Terzopoulos University of California, Los Angeles, CA, USA Doug Tygar University of California, Berkeley, CA, USA Gerhard Weikum Max Planck Institute for Informatics, Saarbrücken, Germany
More information about this series at http://www.springer.com/series/7412
Alejandro F. Frangi Julia A. Schnabel Christos Davatzikos Carlos Alberola-López Gabor Fichtinger (Eds.) Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 21st International Conference Granada, Spain, September 16–20, 2018 Proceedings, Part IV 123
Editors Alejandro F. Frangi University of Leeds Leeds UK Julia A. Schnabel King’s College London London UK Christos Davatzikos University of Pennsylvania Philadelphia, PA USA Carlos Alberola-López Universidad de Valladolid Valladolid Spain Gabor Fichtinger Queen’s University Kingston, ON Canada ISSN 0302-9743 Lecture Notes in Computer Science ISBN 978-3-030-00936-6 https://doi.org/10.1007/978-3-030-00937-3 ISBN 978-3-030-00937-3 (eBook) ISSN 1611-3349 (electronic) Library of Congress Control Number: 2018909526 LNCS Sublibrary: SL6 – Image Processing, Computer Vision, Pattern Recognition, and Graphics © Springer Nature Switzerland AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface We are very pleased to present the conference proceedings for the 21st International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), which was successfully held at the Granada Conference Center, September 16–20, 2018 in Granada, Spain. The conference also featured 40 workshops, 14 tutorials, and ten challenges held on September 16 or 20. For the first time, we had events co-located or endorsed by other societies. The two-day Visual Computing in Biology and Medicine (VCBM) Work- shop partnered with EUROGRAPHICS1, the one-day Biomedical Workshop Biomedical Information Processing and Analysis: A Latin American perspective partnered with SIPAIM2, and the one-day MICCAI Workshop on Computational Diffusion on MRI was endorsed by ISMRM3. This year, at the time of writing this preface, the MICCAI 2018 conference had over 1,400 firm registrations for the main conference featuring the most recent work in the fields of: – Reconstruction and Image Quality – Machine Learning and Statistical Analysis – Registration and Image Guidance – Optical and Histology Applications – Cardiac, Chest and Abdominal Applications – fMRI and Diffusion Imaging – Neuroimaging – Computer-Assisted Intervention – Segmentation This was the largest MICCAI conference to date, with, for the first time, four volumes of Lecture Notes in Computer Science (LNCS) proceedings for the main conference, selected after a thorough double-blind peer-review process organized in several phases as further described below. Following the example set by the previous program chairs of MICCAI 2017, we employed the Conference Managing Toolkit (CMT)4 for paper submissions and double-blind peer-reviews, the Toronto Paper Matching System (TPMS)5 for automatic paper assignment to area chairs and reviewers, and Researcher.CC6 to handle conflicts between authors, area chairs, and reviewers. 1 https://www.eg.org. 2 http://www.sipaim.org/. 3 https://www.ismrm.org/. 4 https://cmt.research.microsoft.com. 5 http://torontopapermatching.org. 6 http://researcher.cc.
VI Preface In total, a record 1,068 full submissions (ca. 33% more than the previous year) were received and sent out to peer-review, from 1,335 original intentions to submit. Of those submissions, 80% were considered as pure Medical Image Computing (MIC), 14% as pure Computer-Assisted Intervention (CAI), and 6% as MICCAI papers that fitted into both MIC and CAI areas. The MICCAI 2018 Program Committee (PC) had a total of 58 area chairs, with 45% from Europe, 43% from the Americas, 9% from Australasia, and 3% from the Middle East. We maintained an excellent gender balance with 43% women scientists on the PC. Using TPMS scoring and CMT, each area chair was assigned between 18 and 20 manuscripts using TPMS, for each of which they suggested 9–15 potential reviewers. Subsequently, 600 invited reviewers were asked to bid for the manuscripts they had been suggested for. Final reviewer allocations via CMT took PC suggestions, reviewer bidding, and TPMS scores into account, allocating 5–6 papers per reviewer. Based on the double-blind reviews, 173 papers (16%) were directly accepted and 314 papers (30%) were directly rejected – these decisions were confirmed by the handling area chair. The remaining 579 papers (54%) were invited for rebuttal. Two further area chairs were added using CMT and TPMS scores to each of these remaining manu- scripts, who then independently scored these to accept or reject, based on the reviews, rebuttal, and manuscript, resulting in clear paper decisions using majority voting: 199 further manuscripts were accepted, and 380 rejected. The overall manuscript acceptance rate was 34.9%. Two PC teleconferences were held on May 14, 2018, in two different time zones to confirm the final results and collect PC feedback on the peer-review process (with over 74% PC attendance rate). For the MICCAI 2018 proceedings, the 372 accepted papers7 have been organized in four volumes as follows: – Volume LNCS 11070 includes: Image Quality and Artefacts (15 manuscripts), Image Reconstruction Methods (31), Machine Learning in Medical Imaging (22), Statistical Analysis for Medical Imaging (10), and Image Registration Methods (21) – Volume LNCS 11071 includes: Optical and Histology Applications (46); and Cardiac, Chest, and Abdominal Applications (59) – Volume LNCS 11072 includes: fMRI and Diffusion Imaging (45); Neuroimaging and Brain Segmentation (37) – Volume LNCS 11073 includes: Computer-Assisted Intervention (39) grouped into image-guided interventions and surgery; surgical planning, simulation and work flow analysis; and visualization and augmented reality; and Image Segmentation Methods (47) grouped into general segmentation methods; multi-organ segmenta- tion; abdominal, cardiac, chest, and other segmentation applications. We would like to thank everyone who contributed greatly to the success of MICCAI 2018 and the quality of its proceedings. These include the MICCAI Society, for support and insightful comments; and our sponsors for financial support and their presence on site. We are especially grateful to all members of the Program Committee for their diligent work in the reviewer assignments and final paper selection, as well as the 600 7 One paper was withdrawn.
Preface VII reviewers for their support during the entire process. Finally, and most importantly, we thank all authors, co-authors, students, and supervisors, for submitting and presenting their high-quality work which made MICCAI 2018 a greatly enjoyable, informative, and successful event. We are especially indebted to those reviewers and PC members who helped us resolve last-minute missing reviews at a very short notice. We are looking forward to seeing you in Shenzhen, China, at MICCAI 2019! August 2018 Julia A. Schnabel Christos Davatzikos Gabor Fichtinger Alejandro F. Frangi Carlos Alberola-López Alberto Gomez Herrero Spyridon Bakas Antonio R. Porras
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